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IκB-alpha Polyclonal Antibody, 20ul[BT-AP10545] Sample Library Tubes It is involved in beta-amyloid

SKU: 80906803468

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PLN111.00 PLN155.00

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IκB-alpha Polyclonal Antibody, 20ul[BT-AP10545] Sample Library Tubes It is involved in beta-amyloidThis gene encodes a member of the NF kappa B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF kappa B REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1 mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T cell

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Description

It is involved in beta-amyloid toxicity and Alzheimer's disease

some of which have been characterized by the presence or absence of an ALU cassette insert and a short or long C-terminal region

The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface

Osteoporosis is characterized by reduced bone mineral density| disrutption of bone microarchitecture| and the alteration of the amount and variety of non-collagenous proteins in bone

the interaction occurs in interphase and is lost upon mitotic entry

IκB-alpha Polyclonal Antibody, 20ul[BT-AP10545] Sample Library Tubes It is involved in beta-amyloidThis gene encodes a member of the NF kappa B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF kappa B REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1 mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T cell

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