Presenilin 2 Rabbit Polyclonal Antibody, 20ul Protein Expression Accessory subunit of the mitochondrial

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I)

The protein interacts with γ-tubulin through its coiled coil domains to localize at the centrosome

The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family

This gene encodes a peptidoglycan recognition protein

Defects in this gene are a cause of female-specific osteoarthritis (OA) susceptibility

Presenilin 2 Rabbit Polyclonal Antibody, 20ul Protein Expression Accessory subunit of the mitochondrialAlzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1 or PSEN2) or the amyloid precursor protein (APP). These disease linked mutations result in increased production of the longer form of amyloid beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma secretase an enzyme that cleaves APP. Also