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Troponin I-C Polyclonal Antibody, 100ul[BT-AP09224] Culture Media Binding to the H1F0 promoter

SKU: 79087537536

4.2
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Troponin I-C Polyclonal Antibody, 100ul[BT-AP09224] Culture Media Binding to the H1F0 promoterTroponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: tnI skeletal fast twitch, TnI skeletal slow twitch, and TnI cardiac. TNNI3 encodes the TnI cardiac protein and is exclusively expressed

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Description

Binding to the H1F0 promoter is enhanced by interaction with RB1

which is considered to be an important tumor suppressor gene region

Three major classes of transcripts are generated from this gene- melanoma inhibitory activity 2-specific transcripts

The protein encoded by this gene is a member of the immunoglobulin binding factor family

Mutations in this gene have been associated with holoprosencephaly type 2

Troponin I-C Polyclonal Antibody, 100ul[BT-AP09224] Culture Media Binding to the H1F0 promoterTroponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: tnI skeletal fast twitch, TnI skeletal slow twitch, and TnI cardiac. TNNI3 encodes the TnI cardiac protein and is exclusively expressed

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