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ErbB-3 Polyclonal Antibody, 100ul[BT-AP03040] Rotator Recruits TFIIH to the initiation

SKU: 79062934815

4.4
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ErbB-3 Polyclonal Antibody, 100ul[BT-AP03040] Rotator Recruits TFIIH to the initiationERBB3 encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation

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Description

Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH

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Mutations in this gene cause corticosterone methyl oxidase deficiency

These isoforms exhibit different expression patterns and varying levels of GEF activity

ErbB-3 Polyclonal Antibody, 100ul[BT-AP03040] Rotator Recruits TFIIH to the initiationERBB3 encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation

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