AVPR1A Polyclonal Antibody, 50ul Measuring Instruments The protein encoded by this

The protein encoded by this gene forms a tetrameric cation channel that is permeable to calcium| sodium| and potassium and is regulated by free intracellular ADP-ribose

GO annotations related to this gene include calcium ion binding

Members of this family metabolize a wide variety of substrates| including ethanol| retinol| other aliphatic alcohols| hydroxysteroids| and lipid peroxidation products

A pseudogene associated with this gene is located on chromosome 12

It is predicted to have a cytoplasmic C-terminus| 13 transmembrane domains| and 3 large loops in the lumen of the endosome - the last loop being at the N-terminus

AVPR1A Polyclonal Antibody, 50ul Measuring Instruments The protein encoded by thisThe protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G protein coupled receptors which includes AVPR1B, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol calcium second messenger system. The receptor mediates cell contraction and proliferation, platelet aggregation, release of coagulation factor and glycogenolysis.