COMP Rabbit Polyclonal Antibody, 50ul Dialysis Histamine regulates several physiologic processes

Histamine regulates several physiologic processes

and many specific SCF substrates have been identified including regulators of cell cycle progression and development

domains III and V contain several EGF-like repeats

May be involved in Rab6-mediated GTPase signaling

Alternative splice variants have been identified| both encoding the same protein

COMP Rabbit Polyclonal Antibody, 50ul Dialysis Histamine regulates several physiologic processesThe protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits each with EGF like and calcium binding (thrombospondin like) domains. Oligomerization results from formation of a five stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Contraction or expansion of a 5 aa aspartate repeat and other mutations