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XG Polyclonal Antibody, 50ul Vector Construction Members of the ADAM family

SKU: 76802682250

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XG Polyclonal Antibody, 50ul Vector Construction Members of the ADAM familyThis gene encodes the XG blood group antigen, and is located at the pseudoautosomal boundary on the short (p) arm of chromosome X. The three 5' exons reside in the pseudoautosomal region and the remaining exons within the X specific end. A truncated copy of this gene is found on the Y chromosome at the pseudoautosomal boundary. It is transcribed, but not expected to make a Y chromosome specific gene product. Alternatively spliced transcript variants

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Description

Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains

The protein encoded by NDRG4 is a cytoplasmic protein that is required for cell cycle progression and survival in primary astrocytes and may be involved in the regulation of mitogenic signalling in vascular smooth muscles cells

The gene is biallelically expressed

The RGS domain of this protein interacts with G alpha(s)| accelerates its GTP hydrolysis| and attenuates G alpha(s)-mediated signaling

Krueppel-like factor 11 encoded by KLF11 is a zinc finger transcription factor that binds to SP1-like sequences in epsilon- and gamma-globin gene promoters

XG Polyclonal Antibody, 50ul Vector Construction Members of the ADAM familyThis gene encodes the XG blood group antigen, and is located at the pseudoautosomal boundary on the short (p) arm of chromosome X. The three 5' exons reside in the pseudoautosomal region and the remaining exons within the X specific end. A truncated copy of this gene is found on the Y chromosome at the pseudoautosomal boundary. It is transcribed, but not expected to make a Y chromosome specific gene product. Alternatively spliced transcript variants

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