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ErbB-4 Polyclonal Antibody, 50ul Vacuum Aspirator Multiple transcript variants for this

SKU: 76405060550

4.7
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ErbB-4 Polyclonal Antibody, 50ul Vacuum Aspirator Multiple transcript variants for thisERBB4 is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol 3 kinase binding site and a PDZ domain binding motif. The erb b2 receptor tyrosine kinase 4 binds to and is activated by neuregulins and other factors and induces a variety of cellular

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Description

Multiple transcript variants for this gene exist

Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins

It seems to interact in a multiprotein complex with RbAp48 and HDAC3

and has been linked to primary microcephaly and Alzheimer's disease

IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes| including interferon beta chain genes

ErbB-4 Polyclonal Antibody, 50ul Vacuum Aspirator Multiple transcript variants for thisERBB4 is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol 3 kinase binding site and a PDZ domain binding motif. The erb b2 receptor tyrosine kinase 4 binds to and is activated by neuregulins and other factors and induces a variety of cellular

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