ErbB-3(Phospho Tyr1197) Polyclonal Antibody, 100ul Lysosome This gene encodes a member

This gene encodes a member of the importin-beta family of nuclear transport proteins

This gene resides in the same region of chromosome 3 as members of the transferrin superfamily

Involved in TGF-beta1 inhibition of IkappaB-alpha expression and suppression of TNF-mediated IkappaB-alpha degradation

Several related pseudogenes are located on chromosomes 1

The protein interacts with host cell factor C1

ErbB-3(Phospho Tyr1197) Polyclonal Antibody, 100ul Lysosome This gene encodes a memberThis gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the