BUB1B Polyclonal Antibody, 20ul Pasteur Pipets alternatively spliced form

alternatively spliced form

Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking| intracellular motility| organelle biogenesis| protein folding| and proteolysis

being involved in the suppression of a cilia assembly program

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The encoded products include neuropeptide B-23 and a C-terminally extended form

BUB1B Polyclonal Antibody, 20ul Pasteur Pipets alternatively spliced formThis gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase promoting complex cyclosome (APC C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer.