FAN1 Rabbit Polyclonal Antibody, 50ul Glassware The new amino terminus functions

The new amino terminus functions as a tethered ligand and activates the receptor

PWWP2B (PWWP domain containing 2B) is a 590 amino acid protein that contains a PWWP domain which is involved in protein-protein interactions

In the presence of ATP

the encoded protein is antimicrobial

and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3

FAN1 Rabbit Polyclonal Antibody, 50ul Glassware The new amino terminus functionsThis gene plays a role in DNA interstrand cross link repair and encodes a protein with 5' flap endonuclease and 5' 3' exonuclease activity. Mutations in this gene cause karyomegalic interstitial nephritis. Alternatively spliced transcript variants encoding distinct isoforms have been described.