Raf-1 Polyclonal Antibody, 100ul[BT-AP13531] Drug Development and Evaluation The induction of cyclooxygenase-2 (PTGS2/COX2)

The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity

The protein encoded by this gene belongs to the iodothyronine deiodinase family

and especially for cap-dependent translation of vesicular stomatitis virus mRNAs

angiopoietin-2

This protein may also regulate inflammation and innate immunity

Raf-1 Polyclonal Antibody, 100ul[BT-AP13531] Drug Development and Evaluation The induction of cyclooxygenase-2 (PTGS2/COX2)This gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.