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EGFR(Phospho Thr693) Polyclonal Antibody, 50ul Custom DNA Oligos The binding of this protein

SKU: 75148757495

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EGFR(Phospho Thr693) Polyclonal Antibody, 50ul Custom DNA Oligos The binding of this proteinThe protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.

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Description

The binding of this protein to IL3 depends on the beta subunit

where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development

This putative nuclear transcription factor most likely functions in regulating the response to growth factors

Its two SH3 domains direct complex formation with proline-rich regions of other proteins

Overexpression increases MET activation and promotes invasive growth

EGFR(Phospho Thr693) Polyclonal Antibody, 50ul Custom DNA Oligos The binding of this proteinThe protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.

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