Mouse Erythropoietin Receptor, EPOR ELISA Kit, 96T Recombinant Protein STE20-related kinase adapter protein alpha

STE20-related kinase adapter protein alpha encoded by STRADA contains a STE20-like kinase domain

RHOBTB3 is a member of the evolutionarily conserved RHOBTB subfamily of Rho GTPases

also involved in microtubule bundling and stabilization of existing microtubules

Required for GDF2/BMP9 signaling through SMAD1 in endothelial cells and modulates TGFB1 signaling through SMAD3 (PubMed: 21737454

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Mouse Erythropoietin Receptor, EPOR ELISA Kit, 96T Recombinant Protein STE20-related kinase adapter protein alphaReceptor for erythropoietin. Mediates erythropoietin induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2 STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase.