Sgo1 Polyclonal Antibody, 50ul Custom DNA Oligos CSH1 is located at the

CSH1 is located at the growth hormone locus on chromosome 17 along with four other related genes in the same transcriptional orientation

Tyrosine protein kinases are important regulators of intracellular signal transduction pathways| mediating cellular proliferation| survival| and development

Each member of this family encodes a protein that catalyzes the joining of DNA ends but they each have a distinct role in DNA metabolism

The functional domains of p53 family proteins include an N-terminal transactivation domain| a central DNA-binding domain and an oligomerization domain

disease:A chromosomal rearrangement involving CTNNB1 may be a cause of salivary gland pleiomorphic adenomas (PA)

Sgo1 Polyclonal Antibody, 50ul Custom DNA Oligos CSH1 is located at theShugoshin like 1 encoded by SGOL1 is a member of the shugoshin family of proteins. This protein is thought to protect centromeric cohesin from cleavage during mitotic prophase by preventing phosphorylation of a cohesin subunit. Reduced expression of this gene leads to the premature loss of centromeric cohesion, mis segregation of sister chromatids, and mitotic arrest. Evidence suggests that this protein also protects a small subset of cohesin found