OTX1 Rabbit Polyclonal Antibody, 100ul Immunology A mutation in this gene

A mutation in this gene was associated with microphthalmia| syndromic 13

A deficiency of vitamin A blocks secretion of the binding protein posttranslationally and results in defective delivery and supply to the epidermal cells

and may induce cell death in myeloid leukemias

and regulate the activity of numerous protein kinases of the JNK signaling pathway

FLI1 encodes friend leukemia integration 1 transcription factor containing an ETS DNA-binding domain

OTX1 Rabbit Polyclonal Antibody, 100ul Immunology A mutation in this geneThis gene encodes a member of the bicoid sub family of homeodomain containing transcription factors. The encoded protein acts as a transcription factor and may play a role in brain and sensory organ development. A similar protein in mouse is required for proper brain and sensory organ development and can cause epilepsy. Alternative splicing results in multiple transcript variants.