CTNL1 Polyclonal Antibody, 50ul Centrifuge Tube (Bottle) have been identified in vertebrates

have been identified in vertebrates

Mutations in this gene are associated with Noonan syndrome 5 and LEOPARD syndrome 2

This gene exhibits imprinted expression from the maternal allele in embryonic and extra-embryonic tissues

Members of this family are characterized by an amino-terminal kinase domain and a carboxy-terminal bipartite polo box domain that functions as a substrate-binding motif and a cellular localization signal

This subunit joins with a beta 1 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family

CTNL1 Polyclonal Antibody, 50ul Centrifuge Tube (Bottle) have been identified in vertebratesMay modulate the Rho pathway signaling by providing a scaffold for the Lbc Rho guanine nucleotide exchange factor (ARHGEF1).,induction: Down regulated in cancer pancreatic cells undergoing differentiation and apoptosis.,Belongs to the vinculin alpha catenin family.,subunit: Interacts with ARHGEF1.,tissue specificity: Widely expressed. Expressed at lower level in neural tissues and at the highest level in the adrenal gland.,