ROBO4 Polyclonal Antibody, 100ul High Speed Micro-Centrifuges Defects in this gene are

Defects in this gene are associated with Fuchs endothelial corneal dystrophy and posterior polymorphous corneal dystrophy type 2

one of the transcripts contains a second overlapping ORF

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The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals

Component of the NF-kappa-B p52-c-Rel complex

ROBO4 Polyclonal Antibody, 100ul High Speed Micro-Centrifuges Defects in this gene areReceptor for Slit proteins, at least for SLIT2, and seems to be involved in angiogenesis and vascular patterning. May mediate the inhibition of primary endothelial cell migration by Slit proteins.,Belongs to the immunoglobulin superfamily. ROBO family.,Contains 2 fibronectin type III domains.,Contains 2 Ig like C2 type (immunoglobulin like) domains.,subunit: Interacts with SLIT2 and ENAH.,tissue specificity: Specifically expressed in endothelial