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Ku-70 Polyclonal Antibody, 50ul[BT-AP04893] Serum & Sample Tubes This gene has been linked

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Ku-70 Polyclonal Antibody, 50ul[BT-AP04893] Serum & Sample Tubes This gene has been linkedThe p70 p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single stranded DNA dependent ATP dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with

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Description

This gene has been linked to non-small cell lung cancer

The protein encoded by the orthologous gene in rat is localized to the Golgi complex and can redistribute to microtubules

lymph node and thymus

It is an important component of cAMP-mediated signal transduction during the spermatogenetic cycle

disease:Defects in CDKN2A are a cause of Li-Fraumeni syndrome (LFS)

Ku-70 Polyclonal Antibody, 50ul[BT-AP04893] Serum & Sample Tubes This gene has been linkedThe p70 p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single stranded DNA dependent ATP dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with

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