Human Receptor-interacting Serine/Threonine-protein Kinase 2, PIPK2 ELISA Kit, 96T miRNA / siRNA Synthesis Sequence-specific DNA-binding factor that binds

Sequence-specific DNA-binding factor that binds to the 5-AGGTCTC-3 sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene (By similarity)

This cytokine is also found to promote proliferation and migration of endothelial cells

possibly by interacting with RNA polymerase II and promoting the formation of a transcriptional pre-initiation complex

depending on dimer composition

May act in concert with RAB3A in regulating aspects of synaptic vesicle membrane flow within the nerve terminal

Human Receptor-interacting Serine/Threonine-protein Kinase 2, PIPK2 ELISA Kit, 96T miRNA / siRNA Synthesis Sequence-specific DNA-binding factor that bindsSerine threonine tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD CARD domains. Contributes to the tyrosine phosphorylation of the guanine exchange factor ARHGEF2 through Src tyrosine kinase leading to NF kappaB activation by NOD2. Once recruited, RIPK2 autophosphorylates and undergoes