ErbB-3 Polyclonal Antibody, 50ul[BT-AP03042] Culture Media Mutations in this gene underlie

Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome| Donohue syndrome and Rabson-Mendenhall syndrome

The BAG domains of BAG1

TPO-R deficient mice were severely thrombocytopenic| emphasizing the important

In addition| a SNP in this gene is responsible for determination of human earwax type

This gene contains an upstream open reading frame in the 5' UTR that inhibits expression of the huntingtin gene product through translational repression

ErbB-3 Polyclonal Antibody, 50ul[BT-AP03042] Culture Media Mutations in this gene underlieERBB3 encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation