IP3R-I Polyclonal Antibody, 20ul[BT-AP04604] Bio-Reaction Tube This powerful 10 mL solution

This powerful 10 mL solution boasts 5 units/μL of activity

Mutations in this gene are associated with lipoid proteinosis disorder (also known as hyalinosis cutis et mucosae or Urbach-Wiethe disease) that is characterized by generalized thickening of skin

including roles in the differentiation and arrangement of tissue three-dimensional structure

2000 [PubMed: 11095983])

GO annotations related to this gene include protein kinase binding

IP3R-I Polyclonal Antibody, 20ul[BT-AP04604] Bio-Reaction Tube This powerful 10 mL solutionITPR1 (inositol 1,4,5 trisphosphate receptor type 1) encodes an intracellular receptor for inositol 1,4,5 trisphosphate. Upon stimulation by inositol 1,4,5 trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in ITPR1 cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for ITPR1.