p47-phox(Phospho Ser370) Polyclonal Antibody, 20ul Cryogenic Vials discover new insights

discover new insights

Mutations in TUBA1A cause lissencephaly type 3 (LIS3) - a neurological condition characterized by microcephaly

The protein encoded by this intronless gene is found in the nucleus| where it can inhibit DNA synthesis and promote S phase arrest coupled to apoptosis

and is a receptor for C-C type chemokines

It has been also shown to play an important role in the proliferation and differentiation of B cells

p47-phox(Phospho Ser370) Polyclonal Antibody, 20ul Cryogenic Vials discover new insightsThe protein encoded by this gene is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide anion. Mutations in this gene have been associated with chronic granulomatous disease.