DR4 Polyclonal Antibody, 50ul Isothermal Amplification Members of the F-box protein

Members of the F-box protein family| such as FBXO10| are characterized by an approximately 40-amino acid F-box motif

Mutations of this gene cause carboxylesterase 1 deficiency

it may have a fundamental role in mammalian systems

this enzyme will efficiently methylate the 5' cap of mRNA for enhanced translation and stability

Disruption of this gene may be associated with developmental dyslexia

DR4 Polyclonal Antibody, 50ul Isothermal Amplification Members of the F-box proteinTNF receptor superfamily member 10a encoded by TNFRSF10A is a member of the TNF receptor superfamily. This receptor is activated by tumor necrosis factor related apoptosis inducing ligand (TNFSF10 TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein.