Desmin Monoclonal Antibody(1B12), 50ul Antibodies intracellular N and C termini

intracellular N and C termini

The protein encoded by this gene has similarity to a mouse protein which suggests a role in the insertion of secretory and membrane polypeptides into the endoplasmic reticulum

Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion

Belongs to the FAM22 family

PTM:Phosphorylated on Ser-13 in mitosis

Desmin Monoclonal Antibody(1B12), 50ul Antibodies intracellular N and C terminiThis gene encodes a muscle specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.