Rb Polyclonal Antibody, 50ul[BT-AP07686] Vacuum Filter and axon fasciculation

and axon fasciculation

The protein functions in cap-independent translation of ornithine decarboxylase mRNA

This protein has been shown to form a stable complex with inter-alpha-inhibitor (I alpha I)

reversible oxidation of malate to oxaloacetate in many metabolic pathways

The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export

Rb Polyclonal Antibody, 50ul[BT-AP07686] Vacuum Filter and axon fasciculationThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.