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IL-19 Polyclonal Antibody, 50ul Liquid Handling &Storage Mutations in this gene are

SKU: 70099459065

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IL-19 Polyclonal Antibody, 50ul Liquid Handling &Storage Mutations in this gene areThe protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up regulate the expression of IL6 and TNF alpha and induce apoptosis, which suggests a role of this cytokine in

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Description

Mutations in this gene are associated with an autosomal dominant form of hereditary fibrosing poikiloderma (HFP)

and is expressed in postmitotic-differentiating neurons of the developmental nervous system and neuronal structures associated with plasticity in the adult

The encoded enzyme specifically recognizes and removes M1(Met1)-linked| or linear| ubiquitin chains from protein substrates

this protein forms a kinase complex including TRAF6

but lacks the ability to bind DNA directly

IL-19 Polyclonal Antibody, 50ul Liquid Handling &Storage Mutations in this gene areThe protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up regulate the expression of IL6 and TNF alpha and induce apoptosis, which suggests a role of this cytokine in

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