IKK gamma Polyclonal Antibody, 50ul[BT-AP02164] Peptide Library a mitochondrial inner membrane Ca2+

a mitochondrial inner membrane Ca2+ channel

and to a lesser extent in heart

Both calcium/calmodulin and protein phosphorylation mechanisms control its activity

The product of this gene belongs to the beta subfamily of regulatory subunit B''

Alternate splicing of this gene generates several transcript variants encoding different isoforms

IKK gamma Polyclonal Antibody, 50ul[BT-AP02164] Peptide Library a mitochondrial inner membrane Ca2+This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex which activates NF kappaB resulting in activation of genes involved in inflammation immunity cell survival and other pathways. Mutations in this gene result in incontinentia pigmenti hypohidrotic ectodermal dysplasia and several other types of immunodeficiencies. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome.