ET-1 Polyclonal Antibody, 100ul Cell Biology 2 (PRYSPRY) domain

2 (PRYSPRY) domain

and other APC complex proteins

IL4I1 encodes interleukin 4 induced 1 with limited similarity to L-amino acid oxidase which contains the conserved amino acids thought to be involved in catalysis and binding of flavin adenine dinucleotide (FAD) cofactor

May function in nuclear protein import as nuclear transport receptor

Mutations in this gene have been associated with geroderma osteodysplastica

ET-1 Polyclonal Antibody, 100ul Cell Biology 2 (PRYSPRY) domainEDN1 encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants.