EpoR Polyclonal Antibody, 20ul[BT-AP03025] Insect Expression Mutations in this gene are

Mutations in this gene are associated with erythrocytosis familial type 4

The protein encoded by ELK1 is a nuclear target for the ras-raf-MAPK signaling cascade

a gene expressed in the head and limbs of the developing fruit fly

which is necessary for protein synthesis

Multiple alternatively spliced variants encoding different isoforms have been described

EpoR Polyclonal Antibody, 20ul[BT-AP03025] Insect Expression Mutations in this gene areEPOR encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: ras MAP kinase, phosphatidylinositol 3 kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce