MMP19 (Cleaved-Tyr98) Rabbit Polyclonal Antibody, 20ul Dialysis The encoded protein functions as

The encoded protein functions as a subunit of the tuberous sclerosis TSC1-TSC2 complex which plays a role in the regulation of cellular growth and differentiation

The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins

60S ribosomal protein L36 belongs to the L36E family of ribosomal proteins

Mutations in this gene have been associated with obesity and mood disorders

none of which are predicted to encode a protein product

MMP19 (Cleaved-Tyr98) Rabbit Polyclonal Antibody, 20ul Dialysis The encoded protein functions asalternative products: Additional isoforms seem to exist Catalytic activity: Cleaves aggrecan at the 360 Ser Phe 361 site. cofactor: Binds 1 zinc ion per subunit. cofactor: Calcium. disease: May play a role in pathological processes participating in rheumatoid arthritis (RA) associated joint tissue destruction. Autoantigen anti MMP19 are frequent in RA patients. The conserved cysteine present in the cysteine switch motif binds the catalytic zinc ion