Human Interleukin 1 Receptor Antagonist, IL1RA ELISA Kit, 96T Gel & Buffers promotes the ZBP1-mediated activation of

promotes the ZBP1-mediated activation of programmed cell death pathways including pyroptosis

It is expressed at low levels in the cytoplasm of pro-B and pre-B cells and present on the cell surface only at mature stages of B-cell differentiation

Expression of this protein also protects cells from DNA damaging reactive oxygen species and provides some protection from DNA damage-induced apoptosis

the activity of the encoded protein depends on the protein binding partner

The protein is primarily localized to membrane-associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus

Human Interleukin 1 Receptor Antagonist, IL1RA ELISA Kit, 96T Gel & Buffers promotes the ZBP1-mediated activation of