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Shc(Phospho Ser36) Polyclonal Antibody, 100ul Adeno-associated Virus Packaging Pseudogenes of this gene are

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Shc(Phospho Ser36) Polyclonal Antibody, 100ul Adeno-associated Virus Packaging Pseudogenes of this gene areThis gene encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways, the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms, p52Shc and p46Shc, link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2 SOS complex. p66Shc is not involved in Ras activation.

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Description

Pseudogenes of this gene are found on multiple chromosomes

Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin

This protein is processed by caspases 7

VEGFA (vascular endothelial growth factor A) is a member of the PDGF/VEGF growth factor family

The encoded protein has been shown to be involved in development of the nervous system

Shc(Phospho Ser36) Polyclonal Antibody, 100ul Adeno-associated Virus Packaging Pseudogenes of this gene areThis gene encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways, the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms, p52Shc and p46Shc, link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2 SOS complex. p66Shc is not involved in Ras activation.

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