Dok-7 Polyclonal Antibody, 100ul Centrifugal Filter Multiple alternatively spliced transcript variants

Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified

The gene of this particular family member is over 10 kb in length

This protein demonstrates oxidoreductase activity toward hydroxysteroids and is able to convert 3-alpha-tetrahydroprogesterone to dihydroxyprogesterone and 3-alpha-androstanediol to dihydroxyprogesterone in the cytoplasm

confer increased lifetime risk of developing breast or ovarian cancer

The protein encoded by this gene is a cytosolic prolyl endopeptidase that cleaves peptide bonds on the C-terminal side of prolyl residues within peptides that are up to approximately 30 amino acids long

Dok-7 Polyclonal Antibody, 100ul Centrifugal Filter Multiple alternatively spliced transcript variantsThe docking protein 7 encoded by DOK7 is essential for neuromuscular synaptogenesis. The protein functions in aneural activation of muscle specific receptor kinase, which is required for postsynaptic differentiation, and in the subsequent clustering of the acetylcholine receptor in myotubes. This protein can also induce autophosphorylation of muscle specific receptor kinase. Mutations in DOK7 are a cause of familial limb girdle myasthenia autosomal