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Lck(Phospho Ser540) Polyclonal Antibody, 20ul Serum Diphthamide is a post-translationally modified

SKU: 65202640169

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Lck(Phospho Ser540) Polyclonal Antibody, 20ul Serum Diphthamide is a post-translationally modifiedThis gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T cells. It contains N terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein protein interactions with phosphotyrosine containing and proline rich motifs, respectively. The protein localizes to the plasma

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Description

Diphthamide is a post-translationally modified histidine residue present in elongation factor 2| and is the target of diphtheria toxin

a member of the tumor necrosis factor family

PFKFB1 encodes a member of the family of bifunctional 6-phosphofructo-2-kinase: fructose-2

Aberrant expression of this gene is associated with intestinal inflammation and tumorigenesis

In addition| protein levels decrease in the presence of natural killer lytic-associated molecule| suggesting that association with natural killer lytic-associated molecule results in ubiquitination and subsequent degradation of this protein

Lck(Phospho Ser540) Polyclonal Antibody, 20ul Serum Diphthamide is a post-translationally modifiedThis gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T cells. It contains N terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein protein interactions with phosphotyrosine containing and proline rich motifs, respectively. The protein localizes to the plasma

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