HAND1 Polyclonal Antibody, 100ul[BT-AP03885] Vessels Defects in TRPS1 are a

Defects in TRPS1 are a cause of tricho-rhino-phalangeal syndrome (TRPS) types I-III

Highest expression seen in the heart and skeletal muscle

where it is involved in transcriptional regulation

CDKN2A generates several transcript variants which differ in their first exons

4 Tube Adapter

HAND1 Polyclonal Antibody, 100ul[BT-AP03885] Vessels Defects in TRPS1 are aThe protein encoded by HAND1 (heart and neural crest derivatives expressed 1) belongs to the basic helix loop helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and