Sgo1 Polyclonal Antibody, 100ul Fluorescent Staining U2AF2 and SNRNP70

U2AF2 and SNRNP70

MIM 611054) for background on liprins

RUNX proteins form a heterodimeric complex with CBFβ which confers increased DNA binding and stability to the complex

It interacts in a complex with chromatin modifying factors

Alternate splice variants have been described but their full length sequences have not been determined

Sgo1 Polyclonal Antibody, 100ul Fluorescent Staining U2AF2 and SNRNP70Shugoshin like 1 encoded by SGOL1 is a member of the shugoshin family of proteins. This protein is thought to protect centromeric cohesin from cleavage during mitotic prophase by preventing phosphorylation of a cohesin subunit. Reduced expression of this gene leads to the premature loss of centromeric cohesion, mis segregation of sister chromatids, and mitotic arrest. Evidence suggests that this protein also protects a small subset of cohesin found