SEM6B Polyclonal Antibody, 50ul Human Genome Knockout Libraries Antiapoptotic protein BCL2-associated athanogene 4

Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor

Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product

DUSP14 contains the consensus DUSP C-terminal catalytic domain but lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class of DUSPs (see MIM 600714) (summary by Patterson et al

The encoded protein contains a potential N-terminal transmembrane domain and a single Armadillo (arm) repeat

Perfect for laboratory use

SEM6B Polyclonal Antibody, 50ul Human Genome Knockout Libraries Antiapoptotic protein BCL2-associated athanogene 4This gene encodes a member of the semaphorin family, a group of proteins characterized by the presence of a conserved semaphorin (sema) domain. Whereas some semaphorins are transmembrane proteins, others are secreted. Semaphorins play a major role in axon guidance. The protein encoded by this gene may be involved in both peripheral and central nervous system development.