DC-LAMP Polyclonal Antibody, 20ul[BT-AP02521] Antibodies Chromosome 17 comprises over 2

Chromosome 17 comprises over 2

Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED)

that is involved in transcription initiation and DNA repair

and may regulate cellular lipid homeostasis in other cell types

and also forms a complex with EPS8 and SOS1 that mediates signal transduction from Ras to Rac

DC-LAMP Polyclonal Antibody, 20ul[BT-AP02521] Antibodies Chromosome 17 comprises over 2Dendritic cells (DCs) are the most potent antigen presenting cells. Immature DCs efficiently capture antigens and differentiate into interdigitating dendritic cells (IDCs) in lymphoid tissues that induce primary T cell responses (summary by de Saint Vis et al. 1998 [PubMed 9768752]).