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RUNX2 Polyclonal Antibody, 20ul[BT-AP08061] Dry Bath The endothelial PAS domain protein

SKU: 60944188637

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RUNX2 Polyclonal Antibody, 20ul[BT-AP08061] Dry Bath The endothelial PAS domain proteinRUNX2 is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA binding domain. Runt related transcription factor 2 is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Two regions

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Description

The endothelial PAS domain protein 1 contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels

PAK5 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton

The encoded enzyme participates in the DNA repair pathway by initiating base excision repair by removing damaged bases

and trapping it in the cytoplasm

thus inhibiting SMAD3-mediated TGF-beta responses

RUNX2 Polyclonal Antibody, 20ul[BT-AP08061] Dry Bath The endothelial PAS domain proteinRUNX2 is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA binding domain. Runt related transcription factor 2 is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Two regions

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