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Phospho-ATRIP (S68) Polyclonal Antibody, 50ul Reservoirs This gene is expressed at

SKU: 60791959007

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Phospho-ATRIP (S68) Polyclonal Antibody, 50ul Reservoirs This gene is expressed atATRIP (ATR interacting protein) encodes an essential component of the DNA damage checkpoint. The encoded protein binds to single stranded DNA coated with replication protein A. The protein also interacts with the ataxia telangiectasia and Rad3 related protein kinase, resulting in its accumulation at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for ATRIP.

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Description

This gene is expressed at significantly lower levels in non-small cell lung cancer cells

and neutralization of pathogens

Patients with mutations in this gene have altered levels of sphingolipid and phospholipids in the brain

which is thought to be associated with human longevity

cyclic nucleotide phosphodiesterase (PDE) family

Phospho-ATRIP (S68) Polyclonal Antibody, 50ul Reservoirs This gene is expressed atATRIP (ATR interacting protein) encodes an essential component of the DNA damage checkpoint. The encoded protein binds to single stranded DNA coated with replication protein A. The protein also interacts with the ataxia telangiectasia and Rad3 related protein kinase, resulting in its accumulation at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for ATRIP.

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