ALX3 Polyclonal Antibody, 100ul Isothermal Amplification The encoded protein acts as

The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma

Induces translational repression through 28S ribosomal RNA cleavage in response to ER stress

IQ calmodulin-binding motif-containing protein 1 has a central coiled-coil region and two calmodulin-binding IQ domains

Alternatively spliced transcript variants have been found for this gene that encode three distinct isoforms

If the protein is bound to a transcriptional insulator element

ALX3 Polyclonal Antibody, 100ul Isothermal Amplification The encoded protein acts asALX3 encodes a nuclear protein (ALX homeobox 3) with a homeobox DNA binding domain that functions as a transcriptional regulator involved in cell type differentiation and development. Preferential methylation of this gene's promoter is associated with advanced stage neuroblastoma tumors.