NALP4 Rabbit Polyclonal Antibody, 50ul Molecular Biologyn Alternative splicing has been observed

Alternative splicing has been observed at this locus and two variants encoding distinct isoforms are described

Unlike most of the other RNA Pol III subunits

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It may function as a bridge molecule between BCL2 and ARHGAP1/CDC42 in promoting cell death

This gene includes a microsatellite repeat in the coding region

NALP4 Rabbit Polyclonal Antibody, 50ul Molecular Biologyn Alternative splicing has been observedNALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs such as NALP4 have an N terminal pyrin (MEFV; MIM 608107) domain (PYD) followed by a NACHT domain a NACHT associated domain (NAD) and a C terminal leucine rich repeat (LRR) region. The long NALP NALP1 (MIM 606636) also has a C terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs