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TLX1 Polyclonal Antibody, 20ul Protein Expression Mutations in this gene may

SKU: 59359739786

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PLN111.00 PLN132.00

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TLX1 Polyclonal Antibody, 20ul Protein Expression Mutations in this gene mayThis gene encodes a nuclear transcription factor that belongs to the NK linked or NK like (NKL) subfamily of homeobox genes. The encoded protein is required for normal development of the spleen during embryogenesis. This protein is also involved in specification of neuronal cell fates. Ectopic expression of this gene due to chromosomal translocations is associated with certain T cell acute lymphoblastic leukemias. Alternate splicing results in

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Description

Mutations in this gene may be associated with dentinogenesis imperfect and autosomal dominant amylogenesis imperfect

and in the prevention of bacterial translocation in the gut

Apoptotic protease-activating factor 1 contains several copies of the WD-40 domain

PPP1R3C (protein phosphatase 1 regulatory subunit 3C) encodes a regulatory subunit of protein phosphatase-1 (PP1)

It functions as a transcriptional co-activator of serum response factor (SRF) and modulates expression of cardiac and smooth muscle-specific SRF-target genes

TLX1 Polyclonal Antibody, 20ul Protein Expression Mutations in this gene mayThis gene encodes a nuclear transcription factor that belongs to the NK linked or NK like (NKL) subfamily of homeobox genes. The encoded protein is required for normal development of the spleen during embryogenesis. This protein is also involved in specification of neuronal cell fates. Ectopic expression of this gene due to chromosomal translocations is associated with certain T cell acute lymphoblastic leukemias. Alternate splicing results in

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