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F111A Rabbit Polyclonal Antibody, 100ul Gloves ZDHHC20 (Zinc Finger DHHC-Type Containing

SKU: 59332301934

4.3
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F111A Rabbit Polyclonal Antibody, 100ul Gloves ZDHHC20 (Zinc Finger DHHC-Type ContainingThe protein encoded by this gene is cell cycle regulated and has nuclear localization. The C terminal half of the protein shares homology with trypsin like peptidases and it contains a PCNA interacting peptide (PIP) box that is necessary for its co localization with proliferating cell nuclear antigen (PCNA). Reduced expression of this gene resulted in DNA replication defects consistent with the demonstrated role for this gene in Simian Virus 40 (SV40)

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Description

ZDHHC20 (Zinc Finger DHHC-Type Containing 20) is a Protein Coding gene

Sterol-C4-mehtyl oxidase-like protein was isolated based on its similarity to the yeast ERG25 protein

This gene encodes a component of a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles

This gene encodes one of the many small GTP-binding proteins in the Rho family shown to be associated with focal adhesions in endothelial cells (PMID: 21148427

Also regulates cholesterol synthesis via phosphorylation and inactivation of hydroxymethylglutaryl-CoA reductase and hormone-sensitive lipase

F111A Rabbit Polyclonal Antibody, 100ul Gloves ZDHHC20 (Zinc Finger DHHC-Type ContainingThe protein encoded by this gene is cell cycle regulated and has nuclear localization. The C terminal half of the protein shares homology with trypsin like peptidases and it contains a PCNA interacting peptide (PIP) box that is necessary for its co localization with proliferating cell nuclear antigen (PCNA). Reduced expression of this gene resulted in DNA replication defects consistent with the demonstrated role for this gene in Simian Virus 40 (SV40)

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