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Stat2 (Acetyl Lys384) Rabbit Polyclonal Antibody, 50ul In vitro Assessment The genes in this cluster

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Stat2 (Acetyl Lys384) Rabbit Polyclonal Antibody, 50ul In vitro Assessment The genes in this clusterSignal transducer and activator of transcription that mediates signaling by type I IFNs (IFN alpha and IFN beta). Following type I IFN binding to cell surface receptors Jak kinases (TYK2 and JAK1) are activated leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize associate with ISGF3G IRF 9 to form a complex termed ISGF3 transcription factor that enters the nucleus. ISGF3 binds to the IFN stimulated response

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Description

The genes in this cluster encode members of the cancer/testis (CT) family of antigens| and are distinct from other CT antigens

Inward rectifier potassium channel 2

Reticulons are necessary for proper generation of tubular endoplasmic reticulum and likely play a role in intracellular vesicular transport

MARK proteins phosphorylate MAPs within their microtubule binding domains

Alternative coreceptor with CD4 for HIV-1 infection

Stat2 (Acetyl Lys384) Rabbit Polyclonal Antibody, 50ul In vitro Assessment The genes in this clusterSignal transducer and activator of transcription that mediates signaling by type I IFNs (IFN alpha and IFN beta). Following type I IFN binding to cell surface receptors Jak kinases (TYK2 and JAK1) are activated leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize associate with ISGF3G IRF 9 to form a complex termed ISGF3 transcription factor that enters the nucleus. ISGF3 binds to the IFN stimulated response

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