MEK-3(Phospho Ser218) Polyclonal Antibody, 100ul Peptide Synthesis A mutation in this gene

A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E

The protein localizes to the nucleoli and interacts with the U3 snoRNP complex

or in stimulating catalytic functions of other subunits during initiation

as well as the synthesis and storage of carbohydrates

Mutations in this gene causes a dominant

MEK-3(Phospho Ser218) Polyclonal Antibody, 100ul Peptide Synthesis A mutation in this geneThe protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase mediated signaling cascade. It phosphorylates and thus activates MAPK14 p38 MAPK. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the