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PDGFR-Beta Polyclonal Antibody, 20ul[BT-AP07021] Micro Centrifuge Tubes is controlled by G-proteins and

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PDGFR-Beta Polyclonal Antibody, 20ul[BT-AP07021] Micro Centrifuge Tubes is controlled by G-proteins andPDGFRB encodes a cell surface tyrosine kinase receptor for members of the platelet derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet derived growth factor receptor alpha and beta polypeptides. PDGFRB is flanked on chromosome 5 by the genes for

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Description

is controlled by G-proteins and plays an important role in regulating heartbeat

Muatations in this gene cause pseudohypoaldosteronism type IID (PHA2D)

When overexpressed in mammalian cells

Expression of SERPINB7 is upregulated in IgA nephropathy and mutations have been found to cause palmoplantar keratoderma

The alpha subunits contain the catalytic activity while the beta subunits undergo autophosphorylation

PDGFR-Beta Polyclonal Antibody, 20ul[BT-AP07021] Micro Centrifuge Tubes is controlled by G-proteins andPDGFRB encodes a cell surface tyrosine kinase receptor for members of the platelet derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet derived growth factor receptor alpha and beta polypeptides. PDGFRB is flanked on chromosome 5 by the genes for

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