Histone H2A.Z (Acetyl Lys14) Rabbit Polyclonal Antibody, 20ul Erlenmeyer Flasks This gene and IL1RAPL1 are

This gene and IL1RAPL1 are located at a region on chromosome X that is associated with X-linked non-syndromic mental retardation

This protein has been implicated in a variety of functions including negative regulation of human airway epithelial barrier formation

Multiple transcript variants encoding different isoforms have been found for this gene| but the biological validity of some variants has not been determined

acts as a pleiotropic cytokine and is involved in the stress reponse program of cells after cellular injury

RAN coactivation of the AR diminishes with polyglutamine expansion within the AR

Histone H2A.Z (Acetyl Lys14) Rabbit Polyclonal Antibody, 20ul Erlenmeyer Flasks This gene and IL1RAPL1 areVariant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation DNA repair DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post translational modifications of histones also called histone