UBP18 Rabbit Polyclonal Antibody, 50ul Yeast Expression Diseases associated with SERPINB5 include

Diseases associated with SERPINB5 include mandibular cancer and laryngeal carcinoma

the region frequently deleted in DiGeorge and velocardiofacial syndromes

Transcript heterogeneity due to alternative polyadenylation has been noted for this gene

and binds copper

excises an intron and encodes the functional protein

UBP18 Rabbit Polyclonal Antibody, 50ul Yeast Expression Diseases associated with SERPINB5 includeThe protein encoded by this gene belongs to the ubiquitin specific proteases (UBP) family of enzymes that cleave ubiquitin from ubiquitinated protein substrates. It is highly expressed in liver and thymus and is localized to the nucleus. This protein efficiently cleaves only ISG15 (a ubiquitin like protein) fusions and deletion of this gene in mice results in a massive increase of ISG15 conjugates in tissues indicating that this protein is a major